Exercise-Related Transient Abdominal Pain (Stitch Pain): A Systematic Review of Mechanisms, Risk Factors, and Management Strategies

Document Type : Original Article

Authors

1 Department of Sport Science Education, Farhangian University, Tehran, Iran

2 Department of Sport Biomechanics, Faculty of Educational Science and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

3 Department of Sport Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

4 Faculty of Educational Science and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

Abstract

Objectives and Study Background:
Exercise-related transient abdominal pain (ETAP) is a common complication among athletes, especially runners, affecting up to 70% of runners. The aim of the present study was to investigate the mechanisms, risk factors, and management strategies for ETAP.
Review Methods and Data Sources:
The present study was a literature review. The search period for articles in Persian and English was from 2000 to 2025, which was conducted in Scopus, PubMed, WOS, Google Scholar, and SID databases. Finally, 19 articles were reviewed based on the inclusion and exclusion criteria.
Findings:
ETAP associated with exercise can be managed with preventative strategies, but if it persists, alternative causes such as median arcuate ligament syndrome should be considered. Some studies have reported a higher incidence of this pain in women, but others have not found a significant association with gender. All studies agree that it gradually decreases with age. Short intervals between meals and exercise, stress, inadequate warm-up, and high intensity of activity are among the contributing factors. Strengthening core muscles and focusing on rhythmic breathing are among the possible contributing factors in preventing this pain.
Conclusion:
Despite the widespread prevalence of this pain, the underlying cause is unclear and research is limited. Due to the limited treatment methods, Further studies are needed to better understand the causative mechanisms, risk factors, and develop targeted therapies.

Keywords

  1. Siahkohian M, Fasihi L, Ebrahimi-Torkmani B. comparison of the effect of aerobic, resistance, and combined exercises on homocysteine serum levels, atherogenic index of plasma, and cardiovascular risk factors in patients with type 2 diabetes. Studies in Medical Sciences. 2024;35(8):621-35.
  2. Khoshraftar Yazdi N, Hakkak Dokht E, Mohajeran ES, Chakani S. Comparison of spinal abnormalities between two groups of clients with exercise related transient abdominal pain (ETAP) and without the side stitch. The Scientific Journal of Rehabilitation Medicine. 2016;5(2):193-200.
  3. Morton D, Callister R. Exercise-related transient abdominal pain (ETAP). Sports medicine. 2015;45(1):23-35.
  4. Morton D, Richards D, Callister R. Epidemiology of exercise-related transient abdominal pain at the Sydney City to Surf community run. Journal of Science and Medicine in Sport. 2005;8(2):152-62.
  5. Morton DP. Exercise related transient abdominal pain. British journal of sports medicine. 2003;37(4):287-8.
  6. Morton DP, Callister R. Characteristics and etiology of exercise-related transient abdominal pain. Medicine and science in sports and exercise. 2000;32(2):432-8.
  7. Shephard RJ. The endurance athlete's" stitch": Etiology and management of exercise-related transient abdominal pain. The Health & Fitness Journal of Canada. 2015;8(3):23-40.
  8. Morton DP, Callister R. Factors influencing exercise-related transient abdominal pain. Medicine & Science in Sports & Exercise. 2002;34(5):745-9.
  9. Coates B, Kowalchik C. Runner's world running on air: The revolutionary way to run better by breathing smarter: Rodale Books; 2013.
  10. Zhang C, Liu C, Pan Z, Wang J. A Pediatric Case of Exercise Related Transient Abdominal Pain (ETAP) and Analysis of Current Literature. Int J Case Rep. 2017;1(01).
  11. Muir B. Exercise related transient abdominal pain: a case report and review of the literature. The Journal of the Canadian Chiropractic Association. 2009;53(4):251.
  12. Mahdalena L, Ferdiansyah A, Putri ne. Eating before exercise causes abdominal cramps: exercise-related transient abdominal pain (etap). Jurnal aorta. 2023;1(02):26-32.
  13. Khoshraftar yn, hakak de. Comparison of vertical displacement of the body and body angles during running in the people with side stitch and healthy people. 2017.
  14. De Oliveira EP, Burini RC, Jeukendrup A. Gastrointestinal complaints during exercise: prevalence, etiology, and nutritional recommendations. Sports Medicine. 2014;44:79-85.
  15. Ter Steege RW, Van Der Palen J, Kolkman JJ. Prevalence of gastrointestinal complaints in runners competing in a long-distance run: an internet-based observational study in 1281 subjects. Scandinavian journal of gastroenterology. 2008;43(12):1477-82.
  16. Morton DP, Callister R. Influence of posture and body type on the experience of exercise-related transient abdominal pain. Journal of Science and Medicine in Sport. 2010;13(5):485-8.
  17. Morton DP, Callister R. EMG activity is not elevated during exercise-related transient abdominal pain. Journal of Science and Medicine in Sport. 2008;11(6):569-74.
  18. Haskins IN, Harr JN, Brody F. Exercise-related transient abdominal pain secondary to median arcuate ligament syndrome: a case report. Journal of Sports Sciences. 2016;34(13):1246-9.
  19. Eichner ER. Stitch in the side: causes, workup, and solutions. Current sports medicine reports. 2006;5(6):289-92.
  20. Waterman JJ, Kapur R. Upper gastrointestinal issues in athletes. Current sports medicine reports. 2012;11(2):99-104.
  21. Pang C, Liang W-Q, Zhang G, Lu T-T, Gao Y-H, Miao X, et al. Prevalence and risk factors of training-related abdominal injuries: A multicenter survey study. Chinese Journal of Traumatology. 2024.
  22. Baart AM, Terink R, Zwerver J, Witteman BJ, Mensink M. Exercise-related abdominal complaints in a large cohort of runners: a survey with a particular focus on nutrition. BMJ open sport & exercise medicine. 2023;9(2):e001571.
  23. Wynne JL, Wilson PB. Thorn in your side or thorn in your head? Anxiety and stress as correlates of exercise-related transient abdominal pain. Clinical Journal of Sport Medicine. 2022;32(5):471-5.
  24. Harr JN, Haskins IN, Brody F. Median arcuate ligament syndrome in athletes. Surgical endoscopy. 2017;31(1):476.
  25. Mole JL, Bird M-L, Fell JW. The effect of transversus abdominis activation on exercise-related transient abdominal pain. Journal of Science and Medicine in Sport. 2014;17(3):261-5.
  26. Morton DP, Callister R. Spirometry measurements during an episode of exercise-related transient abdominal pain. International Journal of Sports Physiology and Performance. 2006;1(4):336-46.
  27. Desmond C, Roberts S. Exercise-related abdominal pain as a manifestation of the median arcuate ligament syndrome. Scandinavian journal of gastroenterology. 2004;39(12):1310-3.
  28. Morton DP, Aragón-Vargas LF, Callister R. Effect of ingested fluid composition on exercise-related transient abdominal pain. International journal of sport nutrition and exercise metabolism. 2004;14(2):197-208.
  29. Capps rb. Cause of the so-called side ache that occurs in normal persons: personal observations. Archives of internal medicine. 1941;68(1):94-101.
  30. Barach AL, Beck GJ. The ventilatory effects of the head-down position in pulmonary emphysema. The American Journal of Medicine. 1954;16(1):55-60.
  31. Darnell MW. A proposed chronology of events for forward head posture. Journal of craniomandibular practice. 1983;1(4):49-54.
  32. Plunkett BT, Hopkins WG. Investigation of the side pain" stitch" induced by running after fluid ingestion. Medicine and science in sports and exercise. 1999;31(8):1169-75.